ANGIOFIBROMA NASAL JUVENIL PDF

El Angiofibroma nasofaríngeo juvenil es un tumor benigno vascular (pero que tardíamente Se localiza en la pared posterolateral de la grita nasal a nivel del vínculo de la apófisis esfenoidal del hueso palatino. Esta localización conforma el. Nasal cavity, paranasal sinuses, nasopharynx – Nasopharyngeal angiofibroma. Juvenile nasopharyngeal angiofibroma (JNA) is a rare and benign but locally in the nasopharynx and nasal cavity, leading to manifestations such as nasal.

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Juvenile nasopharyngeal angiofibroma

jucenil Due to the benign nature of JNAs, the vast majority of these tumors remain extradural even when there is intracranial extension, 9 and the surgical plane is situated between important structures such as the internal carotid artery and cavernous sinus. The excised gross specimen was soft to firm in consistency, white to yellow with darker vascular areas.

Services on Demand Journal. A case report of JNA with rare intra-oral manifestation in a year-old male patient is presented in the article. Sociedade Brasileira de Otorrinolaringologia. Computed tomography CT scan showed the presence of a soft tissue mass involving the maxillary sinus, nasal cavity, and nasopharynx. The success rates and low intra- and postoperative complication rates of endoscopic surgery suggest that this route has been gaining ground in the management of Radkowski IIIa class JNAs.

These lesions include inflammatory polyps, angiomatous polyps, nasopharyngeal cysts and carcinomas, soft tissue neoplasms such as papilloma, lymphoma, neurofibroma, maxillary malignancies, nasal fossa esthesioneuroblastoma, adenoid hypertrophy, cervical vertebrae cordomas and retropharyngeal ganglia angiodibroma. Advanced lesions with orbital and intracranial extension are difficult to treat and may recur often.

Endoscopic and endoscopic-assisted surgery for juvenile angiofibroma.

MRI is used posttreatment to detect residual or recurrent tumor mass and to monitor the effects of radiotherapy. However, most authors agree that JNAs arise from the posterior choanal tissues in the region of the sphenopalatine foramen. National Center for Biotechnology InformationU. Mast cells and T-lymphocytes in juvenile angiofibromas. Non-surgical treatments are available, including the use of hormones estrogen, testosteroneradiation therapy, chemotherapy, and recently, embolization; however, surgery is considered the treatment of choice, with the route depending on the stage of the tumor and the overall condition of the patient 11,12, In this study, immediate complications occurred in two patients who underwent surgery via endoscopic-guided external access.

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Nasopharyngeal angiofibroma – Wikipedia

Intricate mixture of stellate and staghorn blood vessels with variable vessel wall thickness ranging from single layer of endothelium to variable smooth muscle coat Irregular fibrous stroma loose, edematous to dense, acellular Stromal cells are stellate fibroblasts with small pyknotic to large vesicular nuclei Larger vessels at base of lesion, smaller vessels with plump endothelial cells at growing edge of tumor Multinucleated stromal cells are common Mitotic figures are rare Minimal inflammation.

Several surgical approaches have been utilized for the removal of nasopharyngeal angiofibromas, including transnasal, transpalatal, transzygomatic, and transcervical accesses, in addition to lateral rhinotomy and mid-facial degloving, with or without extension to the upper lip or concomitant craniotomy 9. This feature may be helpful is differentiating from other more aggressive lesions.

The disease-free period ranged from 10 to 36 months postoperatively. They may be locally aggressive. Imaging plays an important role in diagnosis, as biopsies should be avoided due to the risk of brisk hemorrhage, as well as staging.

Angiofibroma nasofaríngeo juvenil – Wikipedia, la enciclopedia libre

The recurrence rate of endoscopically resected tumors has been shown to be low, and we found that none of our 20 patients experienced tumor recurrence. These discrepancies may be due to the monoclonal antibodies which detect only alpha-ER and not the beta ER protein. Support Center Support Center. Case 4 Case 4. Therefore, all angiofibromma corresponded to Snyderman grade IV Table 4.

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He had no noteworthy family history or past medical history. Accordingly, the treatment options, operative approach and prognosis can be determined. Author information Article notes Copyright and License information Disclaimer.

Nasopharyngeal angiofibroma

Seventeen patients required clamping of the external carotids and tumor embolization. From a triangular region formed by the foramen ovale, a round and lacerated tumor may reach the middle fossa, migrating to the parasellar region and remaining generally extradual and lateral to the cavernous sinus.

Laterally, these tumors may extend to and fill the pterygomaxillary fossa, causing the posterior nasla of the maxillary sinus to bulge and eroding the pterygoid plate.

Consistent expression of estrogen receptor beta. Eur J Gen Med.

Click here for information on linking to our website or using our content or images. However, in view of the findings of this study, fully endoscopic or endoscopic-guided access should be considered even for advanced-stage tumors with major intracranial extension.

JNA being an aggressive tumor may recur posttreatment. Indian J Dent Res. Although it is a rare neoplasm, juvenile nasopharyngeal angiofibroma JNA is associated with high rates of morbidity and mortality, with the potential for intracranial extension.

In one patient, the procedure had to angiofibrooma halted due to persistent hypovolemic shock despite transfusion, and only partial resection of the tumor was achieved. Patients were aged years.